Table 1.
WKY | SHR | SHR + NAC | |
---|---|---|---|
Body weight (g) | 294.6 ± 4.0 | 308.1 ± 4.5 | 286.9 ± 3.4# |
Heart weight (g) | 1.16 ± 0.06 | 1.38 ± 0.03* | 1.20 ± 0.03# |
Heart weight per 100 g body weight | 0.39 ± 0.02 | 0.45 ± 0.01* | 0.42 ± 0.01 |
Left kidney weight (g) | 1.19 ± 0.05 | 1.36 ± 0.07 | 1.25 ± 0.04 |
Left kidney weight per 100 g body weight | 0.40 ± 0.02 | 0.44 ± 0.02 | 0.43 ± 0.01 |
UNOxV (μmole·24 hr−1·100 g BW−1) | 1.16 ± 0.21 | 0.34 ± 0.15* | 0.69 ± 0.11# |
SHR + NAC, spontaneously hypertensive rat treated with N-acetylcysteine; n = 8 per group; UNOxV, total urinary NOx (NO3 − + NO2 −) excretion. *P < 0.05 SHR versus WKY; # P < 0.05 SHR + NAC versus SHR.