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Metabolic changes associated with abnormal postprandial AUC. The area under the curve of the pressure waves (AUC) was calculated by colonic manometry. Subjects who did not exhibit a normal increase in postprandial AUC had significantly higher median levels of the nine metabolites shown. Kynurenic acid and adenosylhomocysteine levels are significantly higher in all samples except for adenosyl-homocysteine at 30 min.
