TABLE 2.

Multivariate analysis of mapping groups, PFS, and OS—adjusted for age, KPS score, tumor diameter, and histological type^*

		OS			PFS
Group†	No. of Pts	No. of Events	Median FU for Censored (yrs)	HR (95% CI)	No. of Events	Median FU for Censored (yrs)	HR (95% CI)
Noneloquent	107	8	5.6	1.0	37	4.3	1.0
No Mapping	47	28	10	9.0 (3.6–22.3)	35	6.9	1.9 (1.2–3.2)
False-Eloquent	46	7	4.2	2.9 (1.0–8.5)	20	3.8	1.5 (0.9–2.7)
True-Eloquent	81	25	4.0	9.6 (3.6–25.9)	46	3.4	2.5 (1.5–4.3)

^*FU = follow-up.

^†Groups were defined as follows: The Noneloquent Group included all patients with tumors determined to involve only noneloquent areas on the basis of MR imaging. The No Mapping Group included all patients with tumors presumed to involve eloquent areas on the basis of MR imaging who did not undergo intraoperative mapping. The False-Eloquent Group included all those whose tumors were presumed to involve eloquent areas but which were found to spare eloquent brain based on intraoperative mapping. The True-Eloquent Group included all those in whom the presumption of eloquent brain involvement was confirmed through intraoperative mapping.