Figure 2.

Alterations in MAP3K1 genes are observed at relatively low frequency in multiple cancers with prevalent occurrence in luminal A breast cancer. (A) Histogram illustrating the percentage of MAP3K1 alterations for each cancer study: deletion (green), amplification (red), mutation (blue). (B) Alterations of MAP3K1 in the TCGA Breast Invasive Carcinoma data set are predominant in the luminal A, followed by luminal B, breast cancer subtypes. The data were obtained and analyzed by cBioPortal (http://www.cbioportal.org/public-portal/).^64,65