Table 5. Area Under Curve (AUC) values of COSSY and DIRAC for different datasets.

Dataset Name	AUC of COSSY using KEGG	AUC of COSSY using STRING	AUC of DIRAC
Leukemia	0.986	0.985	0.948
CNS	0.862	0.876	0.726
DLBCL	0.985	0.976	0.636
Prostate1	0.909	0.918	0.635
Prostate3	1.000	0.972	1.000
Lung	0.999	0.999	0.990
GCM	0.896	0.889	0.757
Average	0.948	0.945	0.813

AUC has been calculated using the ROCR package in R [35]. The best AUC for each dataset is highlighted in bold face.