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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Mol Cancer Res. 2012 Oct 4;10(12):10.1158/1541-7786.MCR-12-0168. doi: 10.1158/1541-7786.MCR-12-0168

Figure 1.

Figure 1

Analysis with NIH DAVID, Princeton GO term finder and Ingenuity Pathway Analysis yield similar gene enrichments, biological processes and pathways.The high confidence hit list was also analyzed by IPA for biological pathway enrichment. One highly significant network generated by Ingenuity Pathway Analysis containing similar biological processes with other analysis methods is shown. The network is composed of many overlapping genes with genes in the high confidence hit list colored green. Genes not tested in the screen are white while non-sensitizing genes tested in the screen are gray. The top functions in the network are nucleic acid metabolism, small molecule biochemistry and metabolic disease with a network score of 24. The network score is the negative logarithm of the p-value.