TABLE 2.
Organ | Population | No. of leukocytes (106) for indicated phenotype
|
||
---|---|---|---|---|
+/+ | +/− | −/− | ||
Spleen | Total | 98.2 ± 13 | 92.6 ± 20 | 102 ± 35 |
CD4+ T cells | 13.9 ± 1.4 | 14 ± 2.8 | 15.3 ± 4.8 | |
CD8+ T cells | 8.4 ± 0.8 | 8.3 ± 1.7 | 9.4 ± 2.8 | |
B cells | 65 ± 12 | 60.9 ± 14 | 66.3 ± 24 | |
Macrophages (Mac+/Gr−) | 5.5 ± 1.5 | 5.8 ± 1.8 | 5.4 ± 1.3 | |
Neutrophils (Mac+/Gr+) | 1.9 ± 1 | 2.2 ± 0.7 | 1.7 ± 0.7 | |
Lymph node | Total | 3.7 ± 1.1 | 4.5 ± 2.1 | 4 ± 1.6 |
CD4+ T cells | 1.0 ± 0.3 | 1.4 ± 0.6 | 1.2 ± 0.5 | |
CD8+ T cells | 0.8 ± 0.4 | 1.1 ± 0.5 | 1 ± 0.3 | |
B cells | 1.8 ± 0.7 | 1.9 ± 1 | 1.7 ± 0.8 | |
Thymus | Total | 90.4 ± 44 | 148 ± 61 | 132 ± 54 |
CD4+/CD8− | 8 ± 4.1 | 11.7 ± 5.1 | 10 ± 3.2 | |
CD4−/CD8+ | 2.9 ± 1.8 | 3.7 ± 1.4 | 3.3 ± 1.1 | |
CD4+/CD8+ | 74.2 ± 36 | 123 ± 52 | 109 ± 47 |