(A) Triglyceride and cholesterol hepatic content in WT and OPN-deficient mice fed with maltose or ethanol diet (*P<0.05 vs. WT maltose-fed mice, #P<0.05 vs. WT ethanol-fed mice). (B) OPN, TNFα, MCP-1 and IL-6 hepatic gene expression in WT and OPN-deficient mice fed with maltose or ethanol diet (*P<0.05 vs. WT maltose-fed mice, #P<0.05 vs. WT ethanol-fed mice; ND, Non-detected). (C) Serum ALT, AST and triglyceride levels of WT and OPN-deficient mice fed with maltose or ethanol diet (*P<0.01 vs. WT maltose-fed mice, #P<0.05 vs. WT ethanol-fed mice). (D) Serum TNFα, MCP-1 and IL-6 levels of WT and OPN-deficient mice fed with maltose or ethanol diet (*P<0.05 vs. WT maltose-fed mice).