Table 1.

Efficacy to facilitate ICSS as indicated by maximal drug effects on (a) % Baseline Number of Stimulations per Component, and (b) Y-intercept of rate-dependency plots. The dose producing the maximum effect on each measure is also indicated. Doses are expressed in mg/kg, and data for % Baseline Stimulations and Y-Intercepts are given as mean (95% CL). Values were considered to be significantly different if 95% confidence limits did not overlap.

Drug	Dose	Maximum % Baseline Stimulations	Dose	Maximum Y- Intercept
Methcathinone	1.0	192 (147–237)	1.0	0.86 (0.80–0.92)
MDPV	3.2	150 (105–196)	3.2	0.84 (0.82–0.86)
Methylone	10	148 (117–180)	10	0.78 (0.72–0.84)
Mephedrone	3.2	102* (87–118)	10	0.36* (0.30–0.43)

^*Significantly different from methcathinone as indicated by non-overlapping 95% confidence limits.