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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Cogn Neurosci. 2013 Oct 21;26(2):10.1162/jocn_a_00501. doi: 10.1162/jocn_a_00501

Figure 1.

Figure 1

COMT and DARPP-32 genotype interaction effects on working memory performance. Graphs depict target discrimination (d′ for targets versus lures; mean ± SEM). Under high working memory load (3-back trials), COMT and DARPP-32 genotype significantly interact to affect d′, according to an inverted-U relationship (F(2, 89)=4.37, p=0.016). A post-hoc ANOVA found a significant effect of DARPP-32 genotype on 3-back target/lure detection in COMTValMet individuals, F(1,39)=6.23, p=0.017.