Table 1. Demographic data by genotype groups.
Values are reported as mean ± standard deviation. Reported p-values reflect COMT × DARPP-32 interaction effects on the variable of interest following 3 (COMT) × 2 (DARPP-32) ANOVAs. Exact p-values reported unless p < 0.001.
| COMT Val/Val D-32 C (n = 15) |
COMT Val/Met D-32 C (n = 20) |
COMT Met/Met D-32 C (n = 9) |
COMT Val/Val D-32 T/T (n=14) |
COMT Val/Met D-32 T/T (n=23) |
COMT Met/Met D-32 T/T (n =16) |
F(2, 91) (p) |
|
|---|---|---|---|---|---|---|---|
| Age (yrs) | 25.5 ± 4.2 | 26.7 ± 5.6 | 25.9 ± 4.2 | 24.8 ± 4.0 | 24.8 ± 4.7 | 25.1 ± 4.6 | 0.18 (0.84) |
| Edu (yrs) | 16.6 ± 1.5 | 16.4 ± 1.4 | 17.0 ± 2.4 | 16.8 ± 2.3 | 16.7 ± 1.6 | 16.1 ± 0.8 | 0.96 (0.39) |
| Subject SES | 44.1 ± 5.3 | 46.1 ± 6.0 | 48.3 ± 4.0 | 46.1 ± 6.2 | 47.2 ± 6.3 | 46.1 ± 5.8 | 0.89 (0.42) |
| Sex (% female) |
53.3 | 50.0 | 77.8 | 35.7 | 60.9 | 68.8 | (0.34) † |
| Ethnicity (% white) |
40 | 55.0 | 66.7 | 92.9 | 91.3 | 87.5 | (0.001) † |
†
p-value represents results of χ2 test. D-32 C, carrier of DARPP-32 C allele; D-32 T/T, DARPP-32 T/T individuals; SES, socioeconomic status; Edu, education.