Skip to main content
. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Neurobiol Dis. 2013 Oct 10;62:10.1016/j.nbd.2013.10.001. doi: 10.1016/j.nbd.2013.10.001

Figure 6.

Figure 6

PGA in an immature neuron from a CD Type IIIb case (CD associated with a ganglioglioma). A. IR-DIC image shows a cluster of immature neurons. B. Based on the current-voltage relationship, the recorded neuron was likely an immature pyramidal neuron as it displayed inward Na+ and Ca2+ currents to depolarizing voltage commands (Cepeda et al., 2003). C. At a holding potential of −70 mV this neuron displayed PGA with a high degree of autocorrelation (A). D. PGA was blocked with BIC. Interestingly, upon washout of the GABAA receptor antagonist PGA occurred in an episodic, rhythmic manner.