Skip to main content
. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Neurobiol Dis. 2013 Oct 10;62:10.1016/j.nbd.2013.10.001. doi: 10.1016/j.nbd.2013.10.001

Figure 7.

Figure 7

Morphological changes associated with PGA. A. Biocytin-filled normal-like pyramidal neuron from a non-CD case with minimal pathology and Chaslin gliosis. No PGA was observed in this neuron. B. Normal-like pyramidal neuron from a CD case that did not display PGA. Morphology was very similar to the normal-like pyramidal neuron from the non-CD case shown in A. No blebbing was observed and spines appeared normal. C. Normal-like pyramidal neuron from a CD case that displayed PGA. Notice severe dendritic atrophy and blebbing. Panels on the right are high magnification images from the same neurons shown in the left panels to better appreciate dendritic spines (A and B) and swellings (C).