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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Psychopharmacology (Berl). 2013 Aug 15;231(1):10.1007/s00213-013-3219-1. doi: 10.1007/s00213-013-3219-1

Table 4.

Regions showing significant group differences for correct recognition (clusters > 10,233 μl, p < .05). In all regions, heavy drinkers showed less response during correctly recognized stimuli compared to light drinkers.

Anatomic Region (BA) MNI Coordinates Activation Mean (SD) Between-Groups Cohen's d Effect Size

x, y, z Heavy Drinkers Light Drinkers
Cluster 1
Left superior temporal gyrus (38, 41) -45, 7, -9 -1.13 (1.43)* 0.67 (1.56)* 1.19
Left insula, inferior frontal gyrus (13, 47) -45, 12, 4 0.41 (0.96) 1.40 (1.25)* 0.87

Cluster 2
Right superior temporal gyrus, insula (38, 22, 13) 54, 7, -11 -0.88 (1.16)* 0.18 (1.35) 0.84

Note: MNI coordinates refer to peak voxels within cluster; Group activation and between groups Cohen's d refer to 8mm spheres centered on peak voxels;

*

single sample t-test shows that BOLD response to correct vs. incorrect encoding significantly different from 0 (p < .05); positive mean indicates activation during correct recognition, negative mean indicates deactivation correct recognition.