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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Immunogenetics. 2013 Oct 6;66(1):10.1007/s00251-013-0730-9. doi: 10.1007/s00251-013-0730-9

Figure 6.

Figure 6

Schematic representation of NAHR between chromosomes possessing one copy of each gene. In the duplicated haplotype, LILRB3 stays intact and the newly formed hybrid gene contains the 3’ end of LILRA6 and is therefore defined as LILRA6 due to its “activating” 3’ end. The reciprocal haplotype retains only a hybrid gene that has the 3’ end of LILRB3, which defines the gene as inhibitory. If the recombinant chromosomes shown in the scheme were involved in further NAHR, the two daughter recombinant chromosomes will always have a single copy of LILRB3, and LILRA6 will either eliminated altogether or it will be present as one copy or multiple tandem copies.