Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ser125 is the NPM ATR phosphorylation site. (A) NPM GST deletion mutants were constructed as described in Materials and Methods and phosphorylated by ATR in vitro. Mutation of Ser125 to alanine (lane 8) completely abolishes phosphorylation by ATR. (B) SDS-polyacrylamide gel electrophoresis of all the recombinant proteins used in the kinase assay (A).
