Table 2.
Proteina | Neub | WTc | Neu/WTf | p valueg | ||
---|---|---|---|---|---|---|
Meand | SDe | Meand | SDe | |||
Innate Immunity | ||||||
Myeloid bactenecin (Neutrophilic granule protein) | 24 | 12.75 | 295 | 33.99 | 0.08 | 0.0034 |
Lactotransferrin precursor | 67 | 45.00 | 278 | 47.77 | 0.24 | 0.0044 |
Annexin A1 | 53 | 13.40 | 218 | 23.58 | 0.24 | 0.0162 |
Lysozyme C type M precursor | 41 | 10.59 | 186 | 23.43 | 0.22 | 0.0033 |
Myeloperoxidase | 67 | 15.48 | 135 | 24.28 | 0.49 | 0.0121 |
Neutrophil gelatinase-associated lipocalin precursor | 17 | 10.71 | 120 | 32.24 | 0.14 | 0.0303 |
Lymphocyte cytosolic protein 1 | 12 | 2.86 | 62 | 0.00 | 0.20 | 0.0366 |
CD177 antigen | 9 | 3.32 | 52 | 5.17 | 0.17 | 0.0258 |
Leukocyte elastase precursor | 5 | 5.14 | 38 | 0.00 | 0.14 | 0.0020 |
Cathelin-related antimicrobial peptide precursor | 0 | 0.00 | 35 | 6.37 | 0.00 | 0.0116 |
S100-A11 | 2 | 3.01 | 30 | 5.52 | 0.06 | 0.0359 |
Antioxidants | ||||||
Peroxiredoxin-5 | 45 | 8.94 | 149 | 17.30 | 0.30 | 0.0001 |
Cytoskeleton and ECM | ||||||
Myosin heavy chain IX | 145 | 14.56 | 334 | 8.63 | 0.43 | 0.0002 |
Filamin, alpha | 18 | 8.35 | 107 | 9.01 | 0.16 | 0.0009 |
Integrin alpha M | 2 | 3.25 | 59 | 0.00 | 0.03 | 0.0098 |
Integrin beta-2 precursor | 5 | 5.21 | 51 | 0.00 | 0.10 | 0.0018 |
Lamin-B receptor | 5 | 0.27 | 27 | 0.00 | 0.19 | 0.0083 |
Talin-1 | 5 | 5.64 | 25 | 0.00 | 0.22 | 0.0141 |
Actin related protein 2/3 complex | 0 | 0.00 | 6 | 0.00 | 0.00 | 0.0002 |
Histones | ||||||
Histone 4 | 349 | 35.50 | 722 | 141.44 | 0.48 | 0.0262 |
Hist1h2bj protein | 135 | 29.69 | 365 | 44.21 | 0.37 | 0.0149 |
Histone cluster 1, H3g | 31 | 14.60 | 67 | 15.63 | 0.46 | 0.0457 |
Heterogeneous nuclear ribonucleoprotein C | 0 | 0.00 | 21 | 5.98 | 0.00 | 0.0268 |
General Cell Processes | ||||||
Alpha-enolase | 81 | 21.19 | 171 | 43.41 | 0.48 | 0.0404 |
Aldo-keto reductase family 1, member A4 | 57 | 7.28 | 149 | 11.70 | 0.39 | 0.0009 |
Nucleoside diphosphate kinase A | 15 | 5.09 | 55 | 3.19 | 0.28 | 0.0258 |
Phosphoglycerate mutase 1 | 14 | 5.36 | 39 | 7.03 | 0.35 | 0.0167 |
Phosphogluconate dehydrogenase | 13 | 3.78 | 36 | 0.00 | 0.35 | 0.0242 |
NADH dehydrogenase (ubiquinone) Fe-S protein 1 | 5 | 5.14 | 19 | 0.00 | 0.27 | 0.0415 |
Miscellaneous | ||||||
Chitinase 3-like protein 3 precursor | 195 | 17.21 | 388 | 28.58 | 0.50 | 0.0005 |
Kidney-specific protein homolog | 102 | 10.18 | 224 | 46.92 | 0.45 | 0.0291 |
Peptidyl-prolyl cis-trans isomerase A | 53 | 8.03 | 148 | 29.75 | 0.36 | 0.0456 |
Rho GDP-dissociation inhibitor 2 | 23 | 12.10 | 99 | 21.34 | 0.23 | 0.0030 |
Selenium binding protein 1 | 21 | 12.02 | 69 | 10.72 | 0.30 | 0.0113 |
14–3–3 protein zeta/delta | 19 | 7.48 | 53 | 3.35 | 0.36 | 0.0061 |
Guanine nucleotide binding protein, alpha inhibiting 2 | 12 | 2.67 | 32 | 0.00 | 0.39 | 0.0182 |
Myeloblastin precursor | 3 | 5.67 | 16 | 5.17 | 0.21 | 0.0488 |
Rpl30 protein | 3 | 2.99 | 13 | 3.18 | 0.26 | 0.0144 |
RAN, member RAS oncogene family | 2 | 3.01 | 11 | 0.00 | 0.16 | 0.0370 |
Guanine nucleotide binding protein, alpha inhibiting 3 | 0 | 0.00 | 11 | 0.00 | 0.00 | 0.0342 |
Protein identification based on UniRef and NCBI database searches.
Neutropenic mouse.
Wildtype mouse.
Mean of the number of spectra detected in the three technical replicate samples analyzed for this condition.
Standard deviation among the number of the spectra detected in the three technical replicate samples analyzed for this condition.
Ratio of the mean of the number of spectra detected in the neutropenic mouse to that in the wildtype mouse.
p-value as obtained by applying Student’s t-test.