. Author manuscript; available in PMC: 2015 Jan 11.

Published in final edited form as: Pathog Dis. 2013 Oct 1;69(1):36–48. doi: 10.1111/2049-632X.12063

Table 4.

Staphylococcal proteins enriched in neutrophil-depleted abscesses

Protein^a	Short name	Newman gene number	WT^b		Neu^c		Neu/WT^f	p value^g
Protein^a	Short name		Mean^d, ^h	SD^e	Mean^d	SD^e
Glycolysis/gluconeogenesis
Alcohol dehydrogenase	Adh1	NWMN_0577	9	5.14	124	23.41	13.28	0.0012
L-lactate dehydrogenase 2	Ldh	NWMN_2499	8	3.61	25	9.09	2.96	0.0425
Enolase	Eno	NWMN_0745	1	0.00	24	5.18	23.77	0.0014
Glyceraldehyde 3-phosphate dehydrogenase 1	GapA	NWMN_0741	2	3.58	10	0.86	4.96	0.0184
Secreted virulence proteins
Leukocidin LukE precursor	LukE	NWMN_1719	1	0.00	78	5.01	77.93	0.0000
Leukocidin/hemolysin toxin	LukS	NWMN_1928	6	6.31	62	10.89	9.84	0.0016
Gamma-hemolysin	HlgC	NWMN_2319	2	3.64	45	9.55	21.50	0.0019
MapN protein	MapN (Eap)	NWMN_1872	17	7.84	39	2.33	2.29	0.0097
Leukocidin LukD precursor	LukD	NWMN_1718	1	0.00	35	15.40	34.87	0.0172
Gamma hemolysin,	HlgB	NWMN_2320	1	0.00	31	7.05	31.08	0.0016
Extracellular matrix and plasma binding protein	Ssp (Emp)	NWMN_0758	1	0.00	5	0.27	5.33	0.0000
Stress
Universal stress protein	Usp2	NWMN_1604	1	0.00	24	4.55	23.79	0.0008
Iron acquisition
Iron-binding protein IsdA	IsdA	NWMN_1041	3	5.17	24	5.18	7.96	0.0079

Protein identification based on UniRef and NCBI databases searches.

Wildtype mouse.

Neutropenic mouse.⁴

Mean of the number of spectra detected in the three technical replicate samples analyzed for this condition.

Standard deviation among the number of the spectra detected in the three technical replicate samples analyzed for this condition.

Ratio of the mean of the number of spectra detected in the neutropenic mouse to that in the wildtype mouse.

p-value as obtained by applying Student’s t-test.

In cases where proteins were not detected, a value of 1 was assigned to enable ratio calculation.