Table 4.
Proteina | Short name | Newman gene number | WTb | Neuc | Neu/WTf | p valueg | ||
---|---|---|---|---|---|---|---|---|
Meand, h | SDe | Meand | SDe | |||||
Glycolysis/gluconeogenesis | ||||||||
Alcohol dehydrogenase | Adh1 | NWMN_0577 | 9 | 5.14 | 124 | 23.41 | 13.28 | 0.0012 |
L-lactate dehydrogenase 2 | Ldh | NWMN_2499 | 8 | 3.61 | 25 | 9.09 | 2.96 | 0.0425 |
Enolase | Eno | NWMN_0745 | 1 | 0.00 | 24 | 5.18 | 23.77 | 0.0014 |
Glyceraldehyde 3-phosphate dehydrogenase 1 | GapA | NWMN_0741 | 2 | 3.58 | 10 | 0.86 | 4.96 | 0.0184 |
Secreted virulence proteins | ||||||||
Leukocidin LukE precursor | LukE | NWMN_1719 | 1 | 0.00 | 78 | 5.01 | 77.93 | 0.0000 |
Leukocidin/hemolysin toxin | LukS | NWMN_1928 | 6 | 6.31 | 62 | 10.89 | 9.84 | 0.0016 |
Gamma-hemolysin | HlgC | NWMN_2319 | 2 | 3.64 | 45 | 9.55 | 21.50 | 0.0019 |
MapN protein | MapN (Eap) | NWMN_1872 | 17 | 7.84 | 39 | 2.33 | 2.29 | 0.0097 |
Leukocidin LukD precursor | LukD | NWMN_1718 | 1 | 0.00 | 35 | 15.40 | 34.87 | 0.0172 |
Gamma hemolysin, | HlgB | NWMN_2320 | 1 | 0.00 | 31 | 7.05 | 31.08 | 0.0016 |
Extracellular matrix and plasma binding protein | Ssp (Emp) | NWMN_0758 | 1 | 0.00 | 5 | 0.27 | 5.33 | 0.0000 |
Stress | ||||||||
Universal stress protein | Usp2 | NWMN_1604 | 1 | 0.00 | 24 | 4.55 | 23.79 | 0.0008 |
Iron acquisition | ||||||||
Iron-binding protein IsdA | IsdA | NWMN_1041 | 3 | 5.17 | 24 | 5.18 | 7.96 | 0.0079 |
Protein identification based on UniRef and NCBI databases searches.
Wildtype mouse.
Neutropenic mouse.4
Mean of the number of spectra detected in the three technical replicate samples analyzed for this condition.
Standard deviation among the number of the spectra detected in the three technical replicate samples analyzed for this condition.
Ratio of the mean of the number of spectra detected in the neutropenic mouse to that in the wildtype mouse.
p-value as obtained by applying Student’s t-test.
In cases where proteins were not detected, a value of 1 was assigned to enable ratio calculation.