. 2014 Jan;204(1):40–45. doi: 10.1192/bjp.bp.112.125468

Table 2.

Multivariable associations examining maternal fitness, pregnancy complications and potentially toxic exposures and Tourette syndrome/chronic tic disorder risk

	Tourette syndrome		Tourette syndrome/chronic tic disorder
	OR (95% CI)	P	OR (95% CI)	P
Maternal fitness^a
Maternal age^b	2.83 (0.81-9.95)	0.10	1.35 (0.47-3.86)	0.58
Parity^c	0.65 (0.41-1.03)	0.07	0.72 (0.54-0.95)	0.02

Pregnancy complications^d
Less than adequate weight gain	4.55 (1.67-12.41)	<0.01	2.05 (1.05-4.00)	0.04
More than adequate weight gain	1.80 (0.72-4.47)	0.21	1.35 (0.81-2.29)	0.25
Medications for vomiting in 2nd trimester	1.13 (0.15-8.41)	0.91	2.13 (0.76-5.96)	0.15

Toxic exposures^d
Smoking in last 2 months of pregnancy	0.93 (0.48-1.80)	0.82	1.20 (0.82-1.77)	0.34
Alcohol use in last 2 months of pregnancy	1.57 (1.05-2.33)	0.03	1.24 (0.94-1.64)	0.12
Cannabis use in last 2 months of pregnancy	4.60 (1.28-16.62)	0.02	1.91 (0.56-6.49)	0.30

^a.

Mutually adjusted for other variables in the model and socioeconomic status level.

^b.

Maternal age odds ratios (ORs) are denoted as change per 10 years of mother’s age.

^c.

Parity is defined as second born or later compared with first born as the reference category.

^d.

Mutually adjusted for other variables in the model, maternal age and socioeconomic status level.