Table 3.

Multivariable associations examining all variables associated with Tourette syndrome or Tourette syndrome/chronic tic disorder in the parental fitness, complications of pregnancy and toxic exposures analyses^a

	Tourette syndrome		Tourette syndrome/chronic tics
	Odds ratio (95% CI)	P	Odds ratio (95% CI)	P
Maternal age	4.31 (0.86-21.67)	0.08	1.42 (0.31-6.43)	0.65
Parity	0.57 (0.31-1.05)	0.07	0.66 (0.45-0.97)	0.03
Less than adequate weight gain	6.66 (1.74-25.51)	<0.01	3.30 (1.43-7.65)	<0.01
More than adequate weight gain	3.03 (0.88-10.39)	0.08	2.03 (1.00-4.11)	0.05
Alcohol use in last 2 months of pregnancy	1.72 (1.13-2.62)	0.01	1.27 (0.95-1.69)	0.11
Smoking in last 2 months of pregnancy	0.99 (0.51-1.92)	0.97	1.25 (0.82-1.89)	0.30
Cannabis use last 2 months of pregnancy	4.30 (1.14-16.22)	0.03	2.01 (0.57-7.01)	0.28

^a.All variables are mutually adjusted for one another and are adjusted for socioeconomic status. Smoking in the last 2 months of pregnancy is included in the model because of its strong association with alcohol and illicit drug use. Maternal age odds ratios are denoted as change per 10 years of mother’s age. Parity is defined as second born or later compared with first born as the reference category.