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Scope of the α-reaction with varying R group.a
a Reaction was performed with 0.2 mmol 5, 0.4 mmol aldehyde, and 50 mol % Cu(OTf)2 at 0 ºC and allowed the temp raise to room temp with overnight stirring. b Isolated yields after column chromatography; dr ratio (α/β) was determined by the proton NMR of crude products.
