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. 2013 Dec 10;11(12):4917–4936. doi: 10.3390/md11124917

Figure 4.

Figure 4

The effect of compound 7 on the proliferation of HeLa cells using RT-CES analysis. The compound displayed a dose dependent cytotoxic tendency at the IC50 obtained by in vitro viability assay, and twice that amount. The lowest concentration, half of IC50 (2.5 µg/mL), displayed cytostatic effects when compared to the untreated cells grown in culture medium only. Actinomycin D (5.6 µM) was used as a positive control for cell death.