TABLE II.
Patient Characteristics Stratified by Tumor p16 Status.
| Characteristic | Total, n=84 | p16 Positive,* n=69 | p16 Negative,* n=4 |
|---|---|---|---|
| Age, yr | |||
| Mean (range) | 56.0 (35–81) | 56.4 (35–81) | 56.3 (45–67) |
| Sex (%) | |||
| Male | 74 (88) | 62 (90) | 3 (75) |
| Female | 10 (12) | 7 (10) | 1 (25) |
| Tumor subsite (%) | |||
| Base of tongue | 46 (55) | 38 (55) | 1 (25) |
| Tonsil and soft palate | 38 (45) | 31 (45) | 3 (75) |
| AJCC stage (%) | |||
| III | 13 (15) | 10 (14) | 2 (50) |
| IV | 71 (85) | 59 (86) | 2 (50) |
| T stage (%) | |||
| T1 | 29 (35) | 24 (35) | 0 (0) |
| T2 | 33 (39) | 25 (36) | 3 (75) |
| T3 | 15 (18) | 13 (19) | 1 (25) |
| T4 | 7 (8) | 7 (10) | 0 (0) |
| N stage (%) | |||
| N0 | 3 (4) | 3 (4) | 0 (0) |
| N1 | 12 (14) | 9 (13) | 2 (50) |
| N2 | 64 (76) | 54 (78) | 1 (25) |
| N3 | 5 (6) | 3 (4) | 1 (25) |
| Smoking status (%) | |||
| Never | 32 (38) | 28 (41) | 0 (0) |
| Ever | 50 (60) | 39 (57) | 4 (100) |
| Unknown | 2 (2) | 2 (3) | 0 (0) |
| Alcohol consumption, oz/wk (%) | |||
| 0–32 | 36 (43) | 29 (42) | 1 (25) |
| >32 | 47 (56) | 39 (57) | 3 (75) |
| Unknown | 1 (1) | 1 (1) | 0 (0) |
*
p16 data available on 73 patients.
AJCC = American Joint Commission on Cancer; T stage = tumor stage; N stage = nodal stage.