Table 2.
Grade 3 and 4 adverse events: NCI CTC v.3
| |
Induction chemotherapy |
Maintenance chemotherapy |
||
|---|---|---|---|---|
|
(N = 61) |
(N = 41) |
|||
| Adverse events | No. of patients | % | No. of patients | % |
| Nausea |
1 |
2 |
0 |
- |
| Vomiting |
1 |
2 |
0 |
- |
| Diarrhea |
9 |
15 |
2 |
5 |
| Mucositis |
0 |
- |
0 |
- |
| Fatigue |
6 |
10 |
1 |
2 |
| Platelet count decreased |
0 |
- |
0 |
- |
| Anemia |
0 |
- |
0 |
- |
| White blood cell decreased |
3 |
5 |
0 |
- |
| Neutropenia |
8 |
13 |
0 |
- |
| (2 grade IV) | ||||
| Febrile neutropenia |
1 |
2 |
0 |
- |
| Hypertension |
3 |
5 |
1 |
2 |
| Hemorrhage |
1 |
2 |
0 |
- |
| Thromboembolic event |
0 |
- |
1* |
2 |
| Palmar-plantar syndrome | 0 | - | 6 | 15 |
*One catheter related deep vein thrombosis.
Grade IV toxicity: the only grade IV toxicity observed was neutropenia.