Table 3.
Impact of the pneumatic device on tracheal cuff pressure and microaspiration of gastric content
| Variables | Continuous control of P cuff n = 64 | Routine care n = 64 | p | OR (95% CI) |
|---|---|---|---|---|
| Recording duration, h |
24 (23–24) |
24 (23–24) |
0.198 |
|
| Mean airway pressure, cm H2O |
13 (11–18) |
13 (11–17) |
0.216 |
|
| Mean Pcuff, cm H2O |
26 (24–28) |
22 (20–28) |
0.017 |
|
| Coefficient of Pcuff variation, % |
5 (3–12) |
19 (15–30) |
<0.001 |
|
| Pcuff 20-30 cm H2O |
|
|
|
|
| yes |
64 (100) |
64 (100) |
NA |
|
| % of recording time |
95 (70–99) |
44 (30–59) |
<0.001 |
|
| Pcuff <20 or >30, cm H2O |
|
|
|
|
| Yes |
41 (66) |
64 (100) |
<0.001 |
|
| Duration >30 min |
33 (51) |
64 (100) |
<0.001 |
|
| Pcuff <20, cm H2O |
|
|
|
|
| Yes |
19 (29) |
60 (93) |
<0.001 |
1.46 (1.23-1.73) |
| Duration > 30 min |
16 (25) |
57 (89) |
<0.001 |
2.63 (1.11-6.21) |
| % of recording time |
0.01 (0–2) |
32 (9–54) |
<0.001 |
|
| Pcuff >30, cm H2O |
|
|
|
|
| Yes |
33 (51) |
62 (96) |
0.001 |
1.57 (1.10-2.24) |
| Duration >30 min |
25 (39) |
54 (84) |
<0.001 |
1.50 (1.11-2.20 |
| % of recording time |
0.9 (0–17) |
14 (4–30) |
<0.001 |
|
| Microaspiration of gastric content |
32 (50) |
38 (59) |
0.238 |
|
| Pepsin, ng/mL |
185 (113–296) |
203 (120–338) |
0.171 |
|
| % of tracheal aspirates positive for pepsin | 29 (0–74) | 45 (0–100) | 0.162 |
Data are frequencies (%) or median (Interquartile range). Pcuff, cuff pressure.
Yes indicates that a patient had the variable at least once.