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. 2013 Dec 23;13:344. doi: 10.1186/1471-244X-13-344

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Copyright © 2013 Humble et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Plasma oxytocin changes in responders and non-responders to SRI or placebo treatment. Mean plasma oxytocin levels (pg/ml) during the first four treatment weeks, among SRI responders (SRI+, n = 16), SRI non-responders (SRI-, n = 11), placebo responder (PLC+, n = 1) and placebo non-responders (PLC-, n = 8), respectively. Mann Whitney statistics were used because of non-normal data distribution. Significant differences were found: at week 4 between all responders and all non-responders (as shown in graph); at week 4 between SRI responders and SRI non-responders; the change from week 1 to week 4 between SRI responders and non-responders (all p < 0.05); for statistical details see Table 3. Missing data: oxytocin at week 1 was missing for the only placebo responder; oxytocin at week 4 was missing in 3 other patients. SRI = serotonin reuptake inhibitor; PLC = placebo. *p < 0.05.