Table 2.
Demographics and clinical characteristics according to baseline plasma oxytocin level
| All patients n = 36 |
Baseline oxytocin level |
|||
|---|---|---|---|---|
| Low mode range: 16.6-24.5 pg/ml n = 13 | Medium mode range: 27.8-40.3 pg/ml n = 17 | High mode range: 50.6-67.0 pg/ml n = 6 | ||
| Sex, males/females, n (% males) |
17/19 (47) |
5/8 (38) |
10/7 (59) |
2/4 (33) |
| Age, years |
40.7 ± 12.7 |
37.6 ± 12.2 |
43.5 ± 12.6 |
39.4 ± 14.7 |
| Cohabiters/singles, n (% cohab.) |
20/16 (44) |
9/4 (31) |
10/7 (41) |
1/5 (83) |
| Any divorce, yes/no, n (% yes) |
10/26 (28) |
5/8 (38) |
5/12 (29) |
0/6 (0) |
| Having children, yes/no, n (% yes) |
18/18 (50) |
5/8 (38) |
10/7 (59) |
3/3 (50) |
| Number of children |
1.0 ± 1.2 |
0.7 ± 0.9 |
1.2 ± 1.4 |
1.0 ± 1.1 |
| Full time work, yes/no, n (% yes) |
13/22 (37) |
4/9 (31) |
7/9 (44) |
2/4 (33) |
| OCD, age of onset, years |
14.5 ± 6.5 |
16.2 ± 4.7 |
13.7 ± 7.6 |
13.0 ± 6.8 |
| OCD duration, years |
26.2 ± 14.8 |
21.4 ± 14.9 |
29.8 ± 13.6 |
26.4 ± 17.1 |
| Familial OCD, yes/no, n (% yes) |
14/10 (58) |
6/3 (67) |
5/6 (45) |
3/1 (75) |
| History of tics, yes/no, n (% yes) |
8/26 (24) |
2/11 (15) |
3/12 (20) |
3/3 (50) |
| Autistic traits, yes/no, n (% yes) |
11/23 (32) |
5/8 (38) |
5/10 (33) |
1/5 (17) |
| History of poor insight, yes/no, n (% yes) |
6/27 (18) |
1/11 (8) |
4/11 (27) |
1/5 (17) |
| Y-BOCS score, baseline |
25.3 ± 5.9 |
23.5 ± 6.2 |
25.5 ± 5.8 |
28.8 ± 4.7 |
| NIMH-GOCS score, baseline |
9.4 ± 2.0 |
8.8 ± 2.2 |
9.6 ± 1.7 |
10.2 ± 2.1 |
| MADRS score, baseline |
12.2 ± 7.8 |
12.2 ± 8.4 |
12.2 ± 8.4 |
12.2 ± 5.9 |
| Previous SRI treatment, yes/no, n (% yes) | 12/24 (33) | 3/10 (23) | 6/11 (35) | 3/3 (50) |
Mean values ± standard deviations unless otherwise stated. In Chi-2 and one-way ANOVA tests, all the comparisons of these three groups were non-significant. However, for cohabitation the overall result was χ2 = 4.7 (2), p = 0.09, and comparison between the highest mode and the merged lower modes resulted in χ2 = 4.4 (1), p = 0.036.
MADRS = Montgomery Åsberg Depression Rating Scale; NIMH-GOCS = National Institute of Mental Health Global Obsessive Compulsive Scale; OCD = obsessive-compulsive disorder; SRI = serotonin reuptake inhibitors; Y-BOCS = Yale-Brown Obsessive Compulsive Scale.