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. Author manuscript; available in PMC: 2014 Jan 2.
Published in final edited form as: Genet Epidemiol. 2010 Jan;34(1):10.1002/gepi.20435. doi: 10.1002/gepi.20435

Figure 3.

Figure 3

Analysis of stages 1 and 2 data from the FUSION study adjusted for age and sex. The top left panel compares the individual estimates of odds ratios between stages 1 and 2; the top right panel compares the combined estimates of odds ratios between meta-analysis and mega-analysis; the bottom left panel compares the standard error estimates between the two methods; and the bottom right panel compares the − log10(p-values) between the two methods. Mega-analysis assumes age and sex effects to be the same between stages 1 and 2 whereas meta-analysis does not. In each panel, the red line indicates where the values on the two axes are equal.