Table 1.
Author | Country | Target population | Emollient | Dose and frequency | Follow up |
---|---|---|---|---|---|
Arora 2005 [14] | India | Neonates <37 weeks and <1500 g | Sunflower oil | 4 times a day (10ml/kg/day) | 28 days |
Darmstadt 2004 [20] | Egypt | Neonates <34 weeks and <72hr old. Gestational age was determined with an average of gestational age values by last menstrual period, per the criteria of Ballard and Dubowitz | Sunflower oil | 3 times a day for 14 days and then 2 times a day (12g/kg/day) | 28 days |
Darmstadt 2005 [11] | Bangladesh | Neonates <33 weeks and <72hr old. Gestational age was identified by doctors, according to the methods described by Dubowitz and Ballard, and on the basis of maternal dates (time from the first day of the last menstrual period); the average of the three measures was used | A. Sunflower seed oil B. Aquaphor |
3 times a day for 14 days and then 2 times a day (12g/kg/day) | 28 days or until discharge if <28 days |
Darmstadt 2008 [21] | Bangladesh | Neonates <33 weeks and <72hr old. Gestational age was identified by doctors, according to the methods described by Dubowitz and Ballard, and on the basis of maternal dates (time from the first day of the last menstrual period); the average of the three measures was used | A. Sunflower seed oil B. Aquaphor |
3 times a day for 14 days and then 2 times a day (12g/kg/day) | 28 days or until discharge if <28 days |
Kumar 2012 [24] | India | Neonates <35 weeks and <1800 g | Sunflower oil | 10ml/kg/day | 28 days |
Salam (Unpublished) [25] | Pakistan | Neonates ≥26 weeks and ≤37 weeks with a birth weight >750g. Gestational age estimated from ultrasound records and Ballard scores at admission | Coconut oil | 2 times a day (10 ml/kg/day) | 28 days |
Sankaranarayanan 2005 [22] | India | Preterm (1500 to 2000g) and term (>2500g) | A. Coconut oil B. Mineral oil |
4 times a day | 31 days |
Soriano 2000 [23] | Brazil | Neonates 28-34 weeks and <1700 g | Soybean oil | 3 times a day (12g/kg/day) | 30 days |