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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Ann Biomed Eng. 2013 Jul 11;41(11):10.1007/s10439-013-0828-0. doi: 10.1007/s10439-013-0828-0

FIGURE 1.

FIGURE 1

Overall multi-scale hierarchy of the human cerebral circulation. (a) Sagittal view of the full brain vasculature model generated in silico by combing image data with constrained constructive optimization. (b) Magnified section of the secondary cortex next to the collateral sulcus in the right temporal lobe, showing the arrangement of the network of pial arteries and veins at the cortical surface. (c) Isolated view of the territories of two draining pial veins supplied by six penetrating arterioles. (d) The construction principles for the computer aided construction and analysis of cerebral blood flow networks. This article is limited to structures ranging from the pial arterioles to the pial veins are discussed.