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. 2013 Dec 20;20(1):94. doi: 10.1186/1423-0127-20-94

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Copyright © 2013 Lin et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of leptin on the left atrial (LA) electrical activity and effects of isoproterenol on control and leptin-treated left atrial (LA) myocytes. A. Examples and average data of the action potential from control (n = 22) LA myocytes and leptin-treated LA myocytes (n = 19). Leptin-treated LA myocytes had longer APD₂₀. B. Examples of isoproterenol-induced DAD (★) from control and leptin-treated LA myocytes. The incidence of isoproterenol-induced DADs from control (n = 24) and leptin-treated (n = 21) LA myocytes. RMP resting membrane potential, APA action potential amplitude, APD₉₀ 90% action potential duration, APD₅₀ 50% action potential duration, APD₂₀ 20% action potential duration. *p < 0.05 versus control LA myocytes.