TABLE A1.
Effect of treatment on body and liver weights of rats used to prepare liver tissue slices.
Inducer treatment | Sex | Final weight (g) | Percent change in body weight& | Liver weight (g) & | Liver-to-final body weight ratio& |
---|---|---|---|---|---|
Phenobarbital (PB) | Female (n=3) | 224 ± 2 | 5.5 ± 1.3 | 10.1 ± 0.4 | 4.5 ± 0.2 |
Male (n=3) | 300 ± 20 | −2.0 ± 7.0 | 16.0 ± 2.0 | 5.3 ± 0.9 | |
Dexamethasone (DEX) | Female (n=3) | 186 ± 6 | −12.0 ± 4.4* | 12.1 ± 0.2* | 6.5 ± 0.3* |
Male (n=3) | 249 ± 4 | −17.0 ± 0.7* | 16.8 ± 0.6 | 6.8 ± 0.2* | |
Control (CTL) | Female (n=3) | 219 ± 4 | 1.3 ± 3.2 | 9.2 ± 0.7 | 4.2 ± 0.3 |
Male (n=2) | 300 ± 30 | 0.0 ± 0.0 | 13.0 ± 2.0 | 4.4 ± 0.4 |
Data are presented as the mean ± standard deviation. One-way ANOVA and post hoc Tukey’s test (SAS software, version 9.3) were used for multiple comparisons.
Percent change in body weight = (Final body weight − Initial body weight)/Initial body weight × 100.
Significantly different from control (CTL) (p < 0.05).