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. 2013 Dec 18;14(1):139. doi: 10.1186/1465-9921-14-139

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Copyright © 2013 Reinmuth et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Overall survival according to applied lines of systemic therapy. Survival rates were calculated from date of diagnosis. Median survival significantly improved with increasing numbers of lines of systemic therapy (p < 0.001). Patients with 0–6 lines of systemic treatment had a median survival of 2.0, 5.3, 8.7, 13.0, 14.1, 21.8, and 39.1 months, respectively.