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. 2013 Dec 18;6:57. doi: 10.1186/1755-8794-6-57

Table 1.

Validation results of each dataset and integration of 5 data sources

 
Artificial linkage interval
Random control
Whole genome
  TOP AUC FE MRR TOP AUC FE MRR TOP AUC FE MRR
ALL (Lasso)
Leave one out
62.47%
90.86%
68.09
8.90%
57.42%
90.78%
57.42
8.34%
29.34%
90.21%
2616.84
7.57%
Ab initio
61.48%
90.61%
67.01
10.98%
56.58%
90.49%
56.58
8.87%
27.87%
89.16%
2484.89
8.09%
ALL (Regular)
Leave one out
56.96%
89.92%
64.25
11.20%
53.69%
90.24%
53.69
9.98%
24.16%
89.01%
2154.80
8.72%
Ab initio
55.47%
89.52%
63.74
11.60%
52.64%
90.02%
52.64
9.65%
23.11%
88.16%
2061.20
9.22%
PPI
Leave one out
47.41%
86.08%
51.66
16.94%
42.07%
82.23%
42.07
18.05%
9.87%
79.78%
880.31
19.46%
Ab initio
44.82%
84.45%
48.85
17.95%
39.29%
80.02%
39.29
20.29%
9.16%
79.05%
816.98
20.08%
KEGG
Leave one out
42.16%
76.02%
46.20
16.36%
35.89%
73.12%
35.89
19.50%
11.48%
62.38%
1023.90
12.93%
Ab initio
41.02%
75.19%
44.91
16.52%
34.20%
71.31%
34.20
20.10%
11.20%
62.20%
998.93
13.01%
GS
Leave one out
40.34%
79.08%
43.97
18.59%
40.20%
74.07%
40.20
15.80%
10.64%
67.26%
948.98
15.09%
Ab initio
40.27%
78.69%
43.89
18.80%
38.45%
72.73%
38.45
16.40%
10.31%
66.03%
919.55
15.65%
GE
Leave one out
23.25%
74.30%
25.34
31.15%
17.44%
69.04%
17.44
29.51%
1.75%
67.61%
156.08
28.79%
Ab initio
22.97%
74.03%
25.04
31.48%
16.53%
68.60%
16.53
29.94%
1.47%
67.12%
131.11
29.21%
GO Leave one out
24.65%
76.99%
26.86
24.94%
20.24%
69.18%
22.24
23.51%
8.05%
61.74%
717.98
22.63%
Ab initio 24.00% 76.81% 26.16 25.08% 20.10% 68.89% 20.13 23.71% 7.47% 61.44% 666.25 22.95%