Table 1.
Clinical variables of the normal and hydrocephalic neonates used in the study
|
Patient groups |
Age (days) |
Sex ratio (male: female) | Site of CSF collection | Source (UK: Pakistan) | |||
|---|---|---|---|---|---|---|---|
| Groups | n | Age range (days after birth) | Mean | SEM | |||
|
Normal |
8 |
8-92 |
24.50 |
9.72 |
5:3 |
Lumber |
0:8 |
|
FOH |
4 |
11-30 |
18.25 |
4.40 |
4:0 |
Lateral ventricle |
1:3 |
|
LOH |
4 |
60-300 |
153.75 |
55.58 |
3:1 |
Lateral ventricle |
0:4 |
|
PHH |
5 |
28-132 |
74.80 |
22.05 |
2:3 |
Lateral ventricle |
5:0 |
| SB/HC | 4 | 5-105 | 41.00 | 22.79 | 2:2 | Lateral ventricle | 4:0 |
Number of patients, age (days post-partum), gender, and national distribution of the patients studied grouped by known aetiology. Late onset hydrocephalus (LOH) and spina bifida with hydrocephalus (SB/HC) infants are somewhat older than the other groups due to the nature of the condition and the time to receiving treatment. All CSF samples were collected from the lateral ventricle except normal samples that were collected by lumbar puncture. Although there is an age range in each group the low number of samples did not allow analysis of age-related changes. FOH: fetal-onset hydrocephalus, PHH: post-haemorrhagic hydrocephalus.