Table 2.
Protein spots showing maximum fold increase in spot intensity during the 12 weeks post infection, where negative symbol (-) indicates a fold decrease in spot intensity, compared to pre-infection on week 0.
| Spot Number | Identification (Uniprot Reference) | Max. Fold Change | Estimated pI | Estimated MW (kD) | MOWSE Score | Peptide Matches | % coverage |
|---|---|---|---|---|---|---|---|
| 19 | Serotransferrin II + Ig heavy chain C region (TRF2SALSA + A46533) | 3.1 | 6.91 | 112 | 821, 65 | 43, 2 | 38, 5 |
| 32 | C1 inhibitor (Q70W32) | 5.4 | 5.21 | 97 | 137 | 6 | 14 |
| 43 | Serotransferrin II (TRF2SALSA) | 4.5 | 7.36 | 91 | 527 | 14 | 19 |
| 45 | Complement factor H (Q2L4Q6) | 10.4 | 8.37 | 91 | 79 | 2 | 3 |
| 47 | Alpha-2 enolase-1 + Complement factor H (Q9DDG6 + Q2L4Q6) | 3.2 | 7.52 | 90 | 111, 94 | 3, 3 | 9, 3 |
| 74 | No significant identification | 4.4 | 4.33 | 81 | |||
| 98 | Apolipoprotein A-I precursor (JH0472) | 2.6 | 4.96 | 76 | 113 | 5 | 23 |
| 146 | Complement component C9 (Q4QZ25) | 2.2 | 5.2 | 70 | 226 | 7 | 17 |
| 150 | Hemopexin-like protein (P79825) | 9.6 | 4.22 | 68 | 64 | 3 | 9 |
| 151 | Transferrin + Ig heavy chain C region (T11749 + A46533) | 1.5 | 7.27 | 68 | 967, 139 | 32, 4 | 35, 12 |
| 201 | Antithrombin + Complement component C9 (Q9PTA8 + Q4QZ25) | - 2.8 | 5.43 | 59 | 156, 196 | 8, 6 | 14, 21 |
| 220 | Hemopexin-like protein + Beta-actin (P79825 + Q4U1U5) | 2.5 | 6.57 | 57 | 166, 107 | 3, 3 | 8, 12 |
| 224 | Hemopexin-like protein (P79825) | 2.2 | 7.5 | 56 | 150 | 7 | 16 |
| 227 | Hemopexin-like protein (P79825) | 1.5 | 6.06 | 56 | 128 | 11 | 14 |
| 249 | Serotransferrin II (TRF2SALSA) | 5.4 | 8.36 | 51 | 101 | 3 | 7 |
| 260 | Serum albumin 2 + Serum albumin 1 (ABONS2 + ABONS1) | - 1.7 | 4.77 | 50 | 364, 320 | 14, 13 | 24, 20 |
| 299 | Enolase (Q7ZZM5) | 5 | 8.03 | 47 | 308 | 14 | 25 |
| 313 | Pyruvatekinase (Q8QGU8) | 3.5 | 7.58 | 46 | 155 | 6 | 11 |
| 317 | Alpha-2 enolase-1 (Q9DDG6) | 7.6 | 7.94 | 45 | 648 | 37 | 53 |
| 326 | Alpha-2 enolase-1 (Q9DDG6) | 5.6 | 7.78 | 45 | 560 | 23 | 42 |
| 328 | Alpha-2 enolase-1 (Q9DDG6) | 5.2 | 7.27 | 44 | 292 | 15 | 39 |
| 342 | Serum albumin 2 (ABONS2) | - 11.1 | 5.54 | 44 | 666 | 32 | 31 |
| 357 | Serum albumin 2 + Complement factorB/C2-B (ABONS2 + Q9DEC8) | 2.4 | 5.2 | 41 | 302, 49 | 13, 3 | 18, 3 |
| 360 | Alpha-2 enolase-1 (Q9DDG6) | 15.3 | 7.77 | 41 | 624 | 28 | 44 |
| 368 | Serum albumin 2 + Serum albumin 1(ABONS2 + ABONS1) | - 2.8 | 4.88 | 40 | 318, 295 | 15, 13 | 19, 16 |
| 381 | Alpha-2 enolase-1 + Creatine kinase (Q9DDG6 + Q8JH38) | 2.8 | 7.28 | 38 | 704, 101 | 30, 5 | 28, 14 |
| 386 | Aldolase (Q804Y1) | 13.8 | 8.72 | 38 | 108 | 3 | 23 |
| 388 | Aldolase (Q804Y1) | 8.1 | 8.62 | 38 | 94 | 1 | 9 |
| 391 | Muscle-type creatine kinase CKM1 (Q8JH39) | 5.1 | 7.35 | 38 | 252 | 9 | 17 |
| 393 | Glyceraldehyde3-phosphate dehydrogenase (O42259) | 15.7 | 8.79 | 38 | 102 | 9 | 36 |
| 394 | Aldolase A (Q8JH72) | 11.8 | 8.82 | 38 | 231 | 11 | 20 |
| 395 | Serotransferrin II (TRF2SALSA) | 2.2 | 6.56 | 38 | 210 | 5 | 9 |
| 440 | Alpha-2 enolase-1(ABONS1) | 4.5 | 6.64 | 36 | 164 | 3 | 9 |
| 442 | Creatine kinase (Q98SS7) | 3 | 7.61 | 36 | 218 | 6 | 17 |
| 444 | Complement C3-1 + Cystein proteinase inhibitor protein (P98093 + Q70SU8) | - 3.1 | 5.4 | 36 | 156, 36 | 10, 2 | 6, 12 |
| 450 | Serotransferrin II precursor (TRF2SALSA) | - 2.6 | 6.79 | 36 | 444 | 15 | 23 |
| 463 | Glyceraldehyde3-phosphate dehydrogenase (Q90ZF1) | 10.6 | 8.98 | 34 | 247 | 18 | 41 |
| 472 | Serum albumin 2 (Q98SS7) | - 3.7 | 4.79 | 34 | 323 | 12 | 19 |
| 473 | Fructose-bisphosphate aldolase (Q4RVI9) | 16.9 | 8.81 | 34 | 98 | 1 | 3 |
| 477 | Aldolase A (Q8JH72) | 10.1 | 8.7 | 33 | 130 | 5 | 18 |
| 479 | Glyceraldehyde 3-phosphate dehydrogenase (O42259) | 7.1 | 8.43 | 33 | 190 | 20 | 34 |
| 493 | Glyceraldehyde 3-phosphate dehydrogenase (O42259) | 11.6 | 8.18 | 33 | 147 | 13 | 12 |
| 494 | Glyceraldehyde 3-phosphate dehydrogenase (Q90ZF1) | 15.3 | 8.2 | 33 | 280 | 13 | 45 |
| 499 | Proteasome (Q7ZVP5) | 8.2 | 8 | 32 | 35 | 1 | 1 |
| 500 | Aldolase A (Q8JH72) | 15.4 | 8.58 | 32 | 110 | 4 | 17 |
| 509 | Serotransferrin II (TRF2SALSA) | - 2.6 | 6.78 | 31 | 250 | 11 | 18 |
| 529 | Alpha-2 enolase-1 (Q9DDG6) | 5 | 7.07 | 30 | 80 | 3 | 11 |
| 545 | Serotransferrin II (TRF2SALSA) | - 5.7 | 6.57 | 28 | 64 | 3 | 5 |
| 548 | Serum albumin 1 (P21848) | - 7 | 6.29 | 27 | 122 | 3 | 7 |
| 556 | Serotransferrin 2 + Immunoglobulin light chain (TRF2 + AAG18369) | - 5.3 | 6.36 | 27 | 404,150 | 18, 7 | 16, 33 |
| 565 | Hemopexin-like protein (P79825) | 7.8 | 6.26 | 26 | 51 | 4 | 8 |
| 568 | Transferrin (Q8AYG2) | - 3.6 | 7.36 | 26 | 285 | 12 | 36 |
| 575 | Apolipoprotein A-I + Ig light chain precursor (JH0472 + AAG18369) | 1.8 | 6.62 | 26 | 188, 76 | 8, 4 | 28, 24 |
| 584 | Malatedehydrogenase1a (B8JMZ0) | 5.8 | 8.88 | 25 | 70 | 1 | 4 |
| 586 | Apolipoprotein A-I (JH0472) | 1.9 | 4.76 | 25 | 262 | 8 | 27 |
| 598 | Apolipoprotein A-I (JH0472) | 1.5 | 5.15 | 24 | 257 | 19 | 42 |
| 602 | No significant identification. | 3.6 | 8.63 | 24 | |||
| 608 | Triosephosphate isomerase (Q70I40) | 2.8 | 8.5 | 24 | 170 | 6 | 22 |
| 613 | Serum albumin 2 (ABONS2) | 2.4 | 8.1 | 24 | 488 | 19 | 23 |
| 623 | Triosephosphate isomerase + Ig light chain (Q70I40 + AAG18369) | 3.4 | 8.57 | 23 | 305, 109 | 10, 5 | 49, 19 |
| 624 | Triosephosphate isomerase (Q70I40) | 2.4 | 8.1 | 23 | 194 | 11 | 50 |
| 626 | Ig light chain (AAG18369) | 2.4 | 7.26 | 23 | 190 | 8 | 24 |
| 627 | Triosephosphate isomerase + Ig light chain constant region (Q70I40 + AAN40739) | 2.6 | 7.53 | 23 | 131, 87 | 5, 4 | 22, 25 |
| 628 | Triosephosphate isomerase (Q70I40) | 3.9 | 7.85 | 23 | 432 | 19 | 65 |
| 642 | Apolipoprotein A-I (JH0472) | 3.8 | 5.57 | 21 | 435 | 27 | 37 |
| 656 | Serotransferrin II (TRF2SALSA) | - 5.3 | 8.63 | 20 | 251 | 6 | 10 |
| 668 | Apolipoprotein A-I (JH0472) | - 4.8 | 5.17 | 19 | 325 | 19 | 34 |
| 669 | Apolipoprotein A-1 (JH0472) | - 4.1 | 5.42 | 19 | 221 | 14 | 32 |
| 687 | Serotransferrin II (TRF2SALSA) | 4.6 | 7.93 | 18 | 199 | 7 | 12 |
| 702 | Prostaglandin D synthase (Q9DFD7) | - 3.3 | 8.16 | 17 | 82 | 1 | 9 |
| 738 | Putative oncoprotein nm 23 (Q2L4Q6) | 7.2 | 7.3 | 14 | 58 | 11 | 22 |
| 741 | Nucleoside diphosphate kinase (Q7ZZQ7) | 4.6 | 6.9 | 14 | 58 | 8 | 22 |