Fig. 7.
KNO3 (8 mmol) supplementation attenuates platelet aggregation in healthy male but not female volunteers. Platelet aggregation assessed by impedance aggregometry of whole blood collected from healthy male volunteers in response to ADP (10 µmol/L) and epinephrine (10 µmol/L) before and 3h post KNO3 (A, C) and KCl (B, D) supplementation and female volunteers (E, G and F, H respectively). Data are expressed as mean±SEM of n=12. Significance shown for Bonferroni post hoc tests between groups as ⁎P<0.05 following one-way ANOVA (ADP, adenosine diphosphate).