Table 3. Changes in Cancer-Related Knowledge and Decisional Conflict Regarding GTa From Pre- to Post-GCb In BDSc and ADSd patients.
| Median [Range]e | p-value** | |||
|---|---|---|---|---|
| Pre-GC | Post-GC | Change (Post-Pre) | ||
| BDS Patients (n = 16) | ||||
| HBOC Knowledge | (n = 16) 7.0 [2-11] | (n = 10) 10.0 [7-15] | (n = 10) 4 0[-1, 8] | .004 |
| Overall Decisional Conflict | (n = 15) 23.4 [0.0, 60.9] | (n = 11) 25.0 [0.0, 100.0] | (n = 10) 3.1[-34, 89] | .748 |
| Uncertainty | (n = 15) 25.0 [0.0, 58.3] | (n = 11) 25.0 [0.0,100.0] | (n = 10) 0.0[-91.7, 33.3] | .625 |
| Informed | (n = 16) 29.2 [0.0, 91.7] | (n = 11) 25.0 [0.0,100.0] | (n = 11) 0.0[-41.7, 75.0] | .383 |
| Values Clarity | (n = 16) 25.0 [0.0, 58.3] | (n = 11) 25.0 [0.0,100.0] | (n = 11) 0.0[-42, 75] | .818 |
| Support | (n = 16) 25.0 [0.0, 50.0] | (n = 11) 16.7 [0.0,100.0] | (n = 11) 8.3[-33, 100] | .406 |
| Perceived Effective Decision Making | (n = 16) 25.0 [0.0, 56.3] | (n = 11) 25.0 [0.0,100.0] | (n = 11) 0.0[-50, 100] | .719 |
| ADS Patients (n = 87) | ||||
| HBOC Knowledge | (n = 85) 7.0 [0-14] | (n = 78) 10.0 [1-14] | (n = 76) 3.0[-10, 11] | <.001 |
| Overall Decisional Conflict | (n = 83) 29.7 [0.0, 68.8] | (n = 78) 18.0 [0.0, 100.0] | (n = 74) -10.2[-48, 100] | .056 |
| Uncertainty | (n = 87) 25.0 [0.0, 91.7] | (n = 80) 16.7 [0.0, 100.0] | (n = 80) 0.0[-100, 75] | .660 |
| Informed | (n = 85) 50.0 [0.0,100.0] | (n = 80) 25.0 [0.0, 100.0] | (n = 78) -25.0[-75, 100] | <.001 |
| Values Clarity | (n = 87) 33.3 [0.0, 100.0] | (n = 81) 25.0 [0.0, 100.0] | (n = 81) -8.3[-75, 100] | .075 |
| Support | (n = 86) 25.0 [0.0, 66.7] | (n = 80) 16.7 [0.0, 100.0] | (n = 79) -8.3[-50, 100] | .206 |
| Perceived Effective Decision Making | (n = 85) 25.0 [0.0, 62.5] | (n = 79) 12.5 [0.0, 100.0] | (n = 77) 0.0[-63, 100] | .989 |
a
GT = Genetic testing.
b
GC = Genetic counseling.
c
BDS = Before definitive surgery.
d
ADS = After definitive surgery.
e
Scores for cancer-related knowledge range from 0 (no items correct) to 11 (all items correct; scores for decisional conflict range from 0 (no decisional conflict) to 100 (extremely high decisional conflict).
**
Wilcoxon signed-rank tests conducted to compare changes in outcomes, including subscales, from pre- to post-GC in BDS and ADS patients