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. 2013 May 15;54(20):2472–2475. doi: 10.1016/j.tetlet.2013.02.095

Table 2.

Scope of the phase-transfer catalyzed MIRC-reaction of 1c with different chalcones

graphic file with name fx3.jpg

Entry Chalcone Ar1 Ar2 Prod. Yielda (%) er b (+/−)
1 2 Ph Ph 3c 82 13:87
2 7 4-ClC6H4 Ph 8 98 12:88
3 9 Ph 4-ClC6H4 10 91 11:89
4 11 Ph 4-FC6H4 12 72 13:87
5 13 3-NO2C6H4 Ph 14 59 9:91
6 15 4-NO2C6H4 Ph 16 58 10:90
7 17 Ph 4-MeC6H4 18 72 16:84
8 19 4-OH-C6H4 Ph 20 Nrc Nd
9 21 Ph 4-OH-C6H4 22 Nrc Nd
10 23 4-MeO-C6H4 Ph 24 Nrc Nd
11 25 Ph 4-MeO-C6H4 26 Nrc Nd
a

Isolated yield.

b

Determined by HPLC using a chiral stationary phase.

c

Only dimerization of 1c.