Table 1.

Biological processes mediated by proteins with increased abundance in ischemic-tolerant brain. Results of bioinformatic analyses for all proteins that change in abundance under different brain ischemic conditions (with statistic relevance as indicated by calculated P values) are provided in table S7.

Proteins increased in tolerant brain*	Proteins increased in tolerant brain only
Small GTPase-mediated signal transduction	Nucleosome assembly
Protein localization	Nucleosome organization
Establishment of protein localization	Chromatin assembly
Macromolecule localization	DNA packaging
Intracellular signaling cascade	Chromatin assembly or disassembly
Protein transport	Protein-DNA complex assembly
Establishment of localization	Cellular component assembly
Localization	Cellular macromolecular complex assembly
Transport	Localization
Vesicle-mediated transport	Protein transport

^*Includes proteins with increased abundance in other ischemic conditions as well. Processes were defined by Gene Ontology (GO) terms. Proteins are matched to GO terms with the use of the MetaCore program. Processes listed in the table are those statistically most relevant (with the smallest P values).