A. Representative radiograms of the gel mobility shift assay showing CRE-DNA binding activity in nuclear fraction in dorsolateral prefrontal cortex (DLPFC) and cingulate gyrus (CG) of two normal controls (NC), two schizophrenic (SZ), and two bipolar (BP) subjects.
B. The mean CRE-DNA binding activity in the DLPFC nuclear fractions of NC (n = 20), SZ (n = 20), and BP (n = 19) subjects and in the CG nuclear fractions of NC (n = 15), SZ (n = 14), and BP (n = 13) subjects. The results are expressed as optical density (O.D.). Values are mean ± SD.
*p < .05