Table 2.
Expression levels of candidate genes on the microarray and in the qPCR confirmation study
| Array data | Norm-OA (9) | AS-SpA (6) | AS-SpA/Norm-OA | p-value | ||
|---|---|---|---|---|---|---|
| MMP3 |
480.66 |
|
2260.32 |
|
4.7 |
0.005255 |
| MMP1 |
199.47 |
|
701.47 |
|
3.51 |
0.001053 |
| DKK3 |
517.49 |
|
190.98 |
|
-2.71 |
0.003263 |
| KREMEN1 |
988.68 |
|
674.73 |
|
-1.46 |
6.50E-03 |
| PTGER4 |
317.58 |
|
393.08 |
|
1.24 |
4.70E-02 |
|
qPCR |
Norm-OA (9) |
SD |
AS-SpA (7) |
SD |
AS-SpA/Norm-OA |
p-value |
| MMP3 |
0.00026 |
0.00058 |
0.00295 |
0.00412 |
11.35 |
0.07 |
| DKK3 |
0.101 |
0.073 |
0.037 |
0.061 |
-2.7 |
0.086 |
| PTGER4 | 66.6 | 62.9 | 126.7 | 50.1 | 1.9 | 0.042 |