Table 7.

Sensitivity, specificity, and area under curve of all-fitted models and combined quadratic and Schwartz formulas to differentiate children with normal (≥90 ml/min per 1.73 m²) from those with abnormal GFR

Fitted Models and Schwartz Formula	Sensitivity (%)	Specificity (%)	AUC (%)
Linear CysC-based model	63	61	72
Inverse CysC-based model	68	53	71
Logarithmic CysC-based model	70	54	71
Quadratic CysC-based model	63	62	72
Linear SCreat-based model	85	60	86
Quadratic SCreat-based model	80	74	86
New combined SCreat and CysC–based quadratic model	80	77	86
Combined SCreat, CysC, and BUN–based quadratic model	80	77	86
New combined SCreat and CysC–based quadratic formula	80	77	86
Combined SCreat and CysC–based logarithmic Schwartz model	81	68	86
Combined SCreat and CysC Schwartz formula	94	20	78

SCreat, serum creatinine; CysC, cystatin C.