Table 2.
Unadjusted hazard ratios for cardiovascular and noncardiovascular mortality according to GFR tertile groups by each formula
| GFR Tertilea | Hazard Ratio | Lower CI | Upper CI | P Value |
|---|---|---|---|---|
| CV deaths | ||||
| CG<9.5 | 1.06 | 0.69 | 1.65 | 0.78 |
| CG=9.5–11.9 | 1.15 | 0.74 | 1.78 | 0.54 |
| MDRD<6.5 | 0.83 | 0.52 | 1.33 | 0.44 |
| MDRD=6.5–8.9 | 1.38 | 0.90 | 2.13 | 0.14 |
| CKD-EPI<6.0 | 0.90 | 0.58 | 1.41 | 0.65 |
| CKD-EPI=6.0–7.9 | 1.26 | 0.81 | 1.95 | 0.31 |
| Non-CV deaths | ||||
| CG<9.5 | 0.99 | 0.67 | 1.48 | 0.97 |
| CG=9.5–11.9 | 1.25 | 0.85 | 1.84 | 0.26 |
| MDRD<6.5 | 0.42 | 0.28 | 0.62 | <0.001 |
| MDRD=6.5–8.9 | 0.70 | 0.48 | 1.00 | >0.05 |
| CKD-EPI<6.0 | 0.49 | 0.33 | 0.73 | <0.001 |
| CKD-EPI=6.0–7.9 | 0.75 | 0.52 | 1.09 | 0.13 |
CI, confidence interval; CV, cardiovascular; CG, Cockcroft and Gault; MDRD, Modification of Diet in Renal Disease; CKD-EPI, Chronic Kidney Disease-Epidemiology Collaboration.
a
Reference group is the tertile with the highest estimated GFR (CG≥12.0 ml/min per 1.73 m2; MDRD≥9.0 ml/min per 1.73 m2; CKD-EPI≥8.0 ml/min per 1.73 m2).