Table 2.
Demographic and clinical characteristics according to the development of AKI by the KDIGO definition during hospitalization
| Characteristic | No AKI | All AKI Stagesa | Stage 1 | Stage 2 | Stage 3 |
|---|---|---|---|---|---|
| Participants, n | 26,122 | 5848 | 4148 | 1001 | 699 |
| Demographic data | |||||
| Age, yr | 50 (35–66) | 64 (52–75) | 64 (53–75) | 62 (52–72) | 64 (52–74) |
| Men, % | 31.9 | 50.4 | 50.3 | 46.0 | 57.1 |
| Race, % | |||||
| White | 71.5 | 79.4 | 79.6 | 79.6 | 78.0 |
| Black | 11.1 | 8.6 | 8.5 | 8.3 | 10.2 |
| Hispanic | 7.8 | 5.2 | 5.5 | 4.5 | 4.7 |
| Other | 9.7 | 6.8 | 6.5 | 7.6 | 7.2 |
| Laboratory values on admissionb | |||||
| Serum creatinine, mg/dl | 0.8 (0.7–1.0) | 1.0 (0.8–1.5) | 1.0 (0.7–1.3) | 1.1 (0.8–1.5) | 1.9 (1.0–3.6) |
| Hemoglobin, g/dl | 11.8 (10.4–13.0) | 11.1 (9.7–12.7) | 11.2 (9.9–12.7) | 11.1 (9.7–12.8) | 10.3 (8.9–11.8) |
| White blood cell count, 1000/μl | 8.7 (6.5–11.6) | 8.9 (6.3–12.8) | 8.7 (6.3–12.4) | 9.6 (6.5–14.1) | 9.3 (5.9–14.3) |
| Platelet count, 1000/μl | 245 (193–311) | 234 (167–315) | 236 (172–315) | 233 (158–319) | 220 (117–310) |
| BUN, mg/dl | 13 (10–18) | 19 (13–31) | 18 (12–27) | 20 (14–33) | 35 (19–63) |
| Sodium, mmol/L | 137 (135–139) | 137 (134–139) | 137 (134–139) | 137 (133–139) | 136 (133–139) |
| CO2, mmol/L | 25 (23–27) | 24 (22–27) | 25 (22–27) | 24 (21–27) | 22 (19–26) |
| Albumin, g/dl | 3.7 (3.3–4.0) | 3.5 (3.0–3.9) | 3.6 (3.1–4.0) | 3.4 (2.9–3.9) | 3.2 (2.8–3.7) |
| Total bilirubin, mg/dl | 0.4 (0.3–0.6) | 0.5 (0.3–0.8) | 0.5 (0.3–0.7) | 0.5 (0.3–0.8) | 0.5 (0.3–1.0) |
Results are presented as medians with interquartile ranges or column percentages. KDIGO, Kidney Disease Improving Global Outcomes.
a
P<0.001 for all comparisons between patients with AKI and without AKI.
b
The following indicate the laboratory values that were missing in patients without AKI and with AKI, respectively: hemoglobin, 31.1% and 1.4%; white blood cell count, 31.1% and 1.4%; platelet count, 31.1% and 1.4%; BUN, 30.5% and 1.1%; sodium, 33.7% and 1.5%; CO2, 33.7% and 1.5%; albumin, 62.4% and 26.1%; total bilirubin, 62.8% and 26.9%; and serum creatinine, 28.5% and 0.0%.