Table 1.
Demographic data for women receiving dialysis during pregnancy 2001–2011.
| Variable | All Women | CBD Group | COD Group | P Value |
|---|---|---|---|---|
| Patients (n) | 73 | 24 | 49 | |
| Median maternal age at conception (IQR) (yr) | 30.1 (26.1–32.3) | 29.9 (23.1–31.9) | 30.6 (26.2–34.4) | 0.30 |
| Maternal age at conception, n (%) | ||||
| <20 yr | 4 (6) | 4 (17) | 0 | 0.01 |
| 20–34 yr | 53 (76) | 18 (75) | 35 (76) | |
| ≥35 yr | 13 (19) | 2 (8) | 11 (24) | |
| Dialysis modality at conception, n (%) | ||||
| HD | 41 (56) | 41 (84) | ||
| PD | 8 (11) | 8 (16) | ||
| Dialysis modality at end of pregnancy, n (%) | ||||
| HD | 64 (88) | 23 (96) | 41 (84) | 0.26 |
| PD | 9 (12) | 1 (4) | 8 (16) | |
| Median time from commencing dialysis to conception (IQR) (mo) | — | — | 12 (6–33) | |
| Median time from conception to commencing dialysis (IQR) (mo) | — | 3.2 (5.1–2.1) | — | |
| Race, n (%) | 0.24 | |||
| Caucasian | 40 (55) | 14 (58) | 26 (53) | |
| Indigenous | 7 (10) | 4 (17) | 3 (6) | |
| Other | 26 (36) | 6 (25) | 20 (41) | |
| Primary kidney disease, n (%) | 0.75 | |||
| Chronic GN | 41 (56) | 12 (50) | 29 (59) | |
| Other | 15 (21) | 6 (25) | 9 (18) | |
| Reflux nephropathy | 17 (23) | 6 (25) | 11 (22) | |
| Median weight (IQR) (kg) | 62.1 (54–85) | 65.2 (59–87) | 60 (53–83) | 0.15 |
| BMI category, n (%) | 0.28 | |||
| <18.5 kg/m2 | 6 (8) | 0 (0) | 6 (13) | |
| 18.5–24.9 kg/m2 | 33 (46) | 10 (42) | 23 (49) | |
| 25–29.9 kg/m2 | 10 (14) | 5 (21) | 5 (11) | |
| 30–34.9 kg/m2 | 11 (15) | 5 (21) | 6 (13) | |
| ≥35 kg/m2 | 11 (15) | 4 (17) | 7 (15) | |
| Current or former smokers, n (%) | 29 (40) | 10 (42) | 19 (39) | 0.90 |
| Diabetes, n (%) | 6 (8) | 2 (8) | 4 (8) | 0.90 |
| Median eGFR at commencement of dialysis (IQR) (ml/min per 1.73 m2) | 12.4 (6–20) | 4.9 (4–6) | <0.01 |
Continuous data were analyzed using Wilcoxon rank-sum tests, and categorical variables were analyzed using Fisher exact test. In women with multiple pregnancies, data were taken from the first pregnancy.
CBD, conception before dialysis; COD, conception on dialysis; IQR, interquartile range; HD, hemodialysis; PD, peritoneal dialysis; BMI, body mass index; eGFR, estimated GFR.