Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Dec 13;11:308. doi: 10.1186/1479-5876-11-308

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Che et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Evaluation of bone related markers in different groups by semi-quantitative scoring were demonstrated. 0: no expression; 1: focal expression; 2: partial expression; 3: circumferential expression. Immunohistochemical result showed that CathepsinK, RANKL and Osteocalcin were abundantly expressed whereas Runx2 was moderately expressed (p < 0.01) in CRF rats. Expression of Runx2, CathepsinK, RANKL and Osteocalcin were significantly down regulated in 2%La group (p < 0.01 vs CRF group). OPG were strongly positive in Control group and significantly down regulated in CRF group (p < 0.01 vs Control group) and up-regulated in 2%La group (p < 0.05 vs CRF group).