Figure 7.

Impact of RGC100 and poly(I:C) on CD1c⁺ DC-mediated T-cell proliferation. CD1c⁺ DCs were cocultured with autologous T cells in the presence or absence of 50 μg/mL RGC100 or poly(I:C). Before coculture, T cells were stained with cell proliferation dye eFluor 670. Cells were incubated for 8 days and harvested and T cell proliferation was determined by flow cytometry. (a) The results of one representative donor out of three performed with similar results are depicted. (b) The results of three different donors are presented as mean ± SEM. Asterisks indicate a statistically significant difference (*P < 0.05).