Table 1.

Comparison of the physicochemical and functional properties of RGC100 and poly(I:C).

	Length	Molecular weight	Chemical structure	Biostabilitya	Agonist of
RGC100	100 bp	64.6 KDa	dsRNA	7 days	TLR3
Poly(I:C)	~1500–8000 bp	~1020–5440 KDa	dsRNA ± ssRNA	<5 minutes	TLR3, RLRsb

  ^aBiostability measured as resistance to serum nuclease; ^bRLR: RIG-I-like receptors.