Table 3.
Comparison of the number of detoxification genes identified in Bombus huntii , in other bees, and in Drosophila melanogaster
| Putative function | Bombus huntii | Bombus terrestris | Bombus impatiens | Apis mellifera | Megachile rotundata | Drosophila melanogaster |
|---|---|---|---|---|---|---|
|
Oxidation and reduction enzymes | ||||||
| Aldehyde dehydrogenases |
5 |
5 |
5 |
6 |
18 |
23 |
| Catalases |
2 |
1 |
2 |
6 |
5 |
3 |
| Cytochrome P450 |
44 |
50 |
49 |
46 |
52 |
85 |
| (CYP4) |
(2) |
(6) |
(5) |
(5) |
(6) |
(22) |
| (CYP6) |
(18) |
(22) |
(22) |
(28) |
(19) |
(22) |
| Glutaredoxins |
2 |
3 |
7 |
4 |
3 |
7 |
| Peroxidases |
16 |
9 |
9 |
17 |
9 |
20 |
| Superoxide dismutases |
2 |
4 |
6 |
5 |
8 |
6 |
|
Conjugation enzymes |
|
|
|
|
|
|
| Acyltransferases |
13 |
28 |
30 |
32 |
8 |
55 |
| Glutathione S-transferases |
11 |
14 |
15 |
18 |
9 |
42 |
| (Sigma-GSTs) |
(3) |
(0/?) |
(0/?) |
(4) |
(1) |
(1) |
| (Epsilon-GSTs) |
(0) |
(0/?) |
(0/?) |
(0) |
(0) |
(10) |
| Sulfotransferases |
2 |
17 |
16 |
17 |
5 |
15 |
| UDP-glucuronosyltransferases |
2 |
6 |
8 |
2 |
2 |
7 |
|
Hydrolytic enzymes |
|
|
|
|
|
|
| Alkaline phosphatases |
1 |
3 |
4 |
3 |
2 |
16 |
| Amidases |
2 |
4 |
8 |
4 |
7 |
12 |
| Aminopeptidases |
12 |
19 |
26 |
24 |
27 |
41 |
| Amylases |
2 |
1 |
1 |
2 |
2 |
15 |
| Carboxylesterases/Esterases |
23 |
17 |
22 |
24 |
22 |
54 |
| Glucosidases |
8 |
7 |
8 |
18 |
5 |
29 |
| Glucuronidases |
1 |
1 |
1 |
1 |
2 |
4 |
| Glycosylases |
3 |
2 |
5 |
7 |
6 |
5 |
| Nitrilases | 25 | 1 | 2 | 3 | 2 | 2 |
Note: The numbers of B. huntii and M. rotundata genes are transcriptome data from 454 pyrosequencing, except for P450 of M. rotundata which is genomic data. The numbers of B. terrestris, B. impatiens, A. mellifera, and D. melanogaster genes are from genomic data from the NCBI GenBank database (http://www.ncbi.nlm.nih.gov/genome, accessed on September 25, 2013), and the numbers in brackets below P450 or GSTs are subgroups of P450 or GSTs.